MyBioSource.com's CKI-alpha Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunofluorescence, Immunohistochemistry, and Western Blot. The CKI-alpha Antibody was generated using CK1A, CK1alpha, and CSNK1A1 as the antigen and it reacts with Human, Mouse, and Rat.
Description
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis.Tapia C., FEBS Lett. 349:307-312(1994).Fish K.J., J. Biol. Chem. 270:14875-14883(1995).Liu C., Cell 108:837-847(2002)